Analysis of the Sox gene family in the European sea bass (Dicentrarchus labrax). | - CCMAR -

Journal Article

TítuloAnalysis of the Sox gene family in the European sea bass (Dicentrarchus labrax).
Publication TypeJournal Article
AuthorsGalay-Burgos, M, Llewellyn, L, Mylonas, CC, Canario, AVM, Zanuy, S, Sweeney, GE
Year of Publication2004
JournalComp Biochem Physiol B Biochem Mol Biol
Date Published2004 Feb
Palavras-chaveAnimals, Base Sequence, Bass, Cloning, Organism, Fish Proteins, High Mobility Group Proteins, HMG-Box Domains, Humans, Mice, Molecular Sequence Data, Phylogeny, Sequence Alignment

Sox (SRY-related genes containing a HMG box) genes encode a family of transcription factors that are involved in a variety of developmental processes including sex determination. Twenty Sox genes are present in the genomes of humans and mice, but far less is known about the Sox gene family in other vertebrate types. We have obtained clones representing the HMG boxes of twelve Sox genes from European sea bass (Dicentrarchus labrax), a fish species whose farming is complicated by a heavily skewed sex ratio, with between 70% and 99% of offspring typically being male. The cloned Sox genes are members of the SoxB, SoxC, SoxE and SoxF groups. Sequence analysis shows that some of the clones represent genes duplicated in sea bass with respect to the mammalian Sox gene family.


Alternate JournalComp. Biochem. Physiol. B, Biochem. Mol. Biol.
PubMed ID14990224
CCMAR Authors